Regulatory Pathways & Sectors · Iterchem
Predictive toxicology for
heavily regulated chemistry.
From preclinical pharmaceutical triage to animal-free cosmetic safety substantiation (NAMs), EndoXplain adapts explainable in silico evidence to the requirements of each sector.
ANVISA · FDA IND · EMA
Pharmaceuticals & APIs
Anticipate off-target endocrine liabilities upstream of medicinal synthesis and costly preclinical wet-lab studies.
- High-throughput in silico triage across virtual libraries and analogue series
- Explainable AI rationale isolating structural drivers of endocrine activity
- Traceable technical reports supporting preclinical stage-gate decisions
MAPA · IBAMA · ANVISA · EPA
Agrochemicals & Crop Protection
Substantiate the endocrine safety of active ingredients, metabolites, and formulation alternatives under stringent registration and re-evaluation mandates.
- Endocrine risk profiling across active ingredients and environmental metabolites
- Explicit uncertainty and reliability quantification per candidate structure
- Auditable PDF reports structured for MAPA, IBAMA, and ANVISA workflows
OECD NAMs · ANVISA · EU Cosmetics
Cosmetics & Personal Care
Replace vertebrate bioassays with 100% cruelty-free, traceable New Approach Methodologies (NAMs) for cosmetic ingredients, UV filters, and fragrances.
- Animal-free endocrine risk screening from chemical structure
- Explainable structural rationale and reliability indicators
- Exportable technical documentation for cosmetic safety dossiers
ANVISA · EFSA TTC
Food Contact & Contaminants
Rapidly qualify Non-Intentionally Added Substances (NIAS), packaging leachables, and polymer additives with defensible computational evidence.
- Rapid hazard triage for uncharacterized migrants and oligomers
- Endocrine structural alert screening integrated with exposure context
- Version-locked audit trail for food-safety regulatory inspections
OECD Guidelines · Chemical R&D
Novel Scaffolds & Ingredients
Embed toxicological stage-gates directly into new molecule discovery and specialty chemical R&D before committing bench synthesis capital.
- Authenticated REST API integration with strict multi-tenant data isolation
- Joint evaluation of biological activity, toxicity, and prediction uncertainty
- Reduced time and cost per decision across novel chemical programs